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Research on Memory and Brain Building


Clinical research has consistently shown that keeping mentally active can help to stave off the effects of cognitive decline. Participating in challenging tasks such as reading and playing games on a daily basis can help with prevent the memory loss associated with dementia, including Alzheimer's disease.

Researchers at Chicago’s Rush Alzheimer's Disease Center studied 801 Catholic nuns and priests over 65 looking at the association between Alzheimer's and cognitively stimulating activities. The researchers observed that people who participated most often in mentally challenging activities had a 47% lower risk of developing Alzheimer's. Those who participated in a moderate amount had a 28% lower risk.

In another study, researchers discovered that the odds of developing Alzheimer's were nearly quadrupled in people who were less active during their leisure time between the ages of 20 and 60 compared with their peers. This was true regardless of the type of activity, although spending time in intellectual pursuits appeared to be the most beneficial.

Researchers at the University of Southern California in Los Angeles studied the effect of leisure activities on the risk of Alzheimer's. They asked 107 same-sex twins about three different types of leisure activities;

  1. Physical activities like sports, working out in a gym, biking, gardening, ice skating, walking, and jogging.
  2. Intellectual activities like reading, doing puzzles, playing a musical instrument, painting, woodworking, playing cards or board games, and performing home repairs.
  3. Passive activities like watching television, listening to music, attending social clubs, talking on the phone, visiting with friends and attending religious services.
Investigators took into account factors that influence the risk of Alzheimer's, including age, sex, education, and socioeconomic status and found that people who participated in fewer activities than the average were 3.85 times more likely to develop Alzheimer's. Those who partook in the most intellectually stimulating activities had the lowest risk.

These findings are best explained by the cognitive reserve hypothesis, which proposes that both increased brain volume and enhanced cognitive ability may contribute to healthy brain aging, reducing the likelihood of developing Alzheimer's and other dementias.

Other research has suggested that new cells can generate in the brain, and learning stimulates their growth. The adage "use it or lose it" may apply to your brain as well as your body, brain experts say. Given the state of the research, doctors who study Alzheimer's disease say people worried about their memories should eat right, exercise, and have fun using their brains with programs like Brain Builder® Memory Software and other types of mental calisthenics.

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Koepsell TD, Kurland BF, Harel O, Johnson EA, Zhou XH, Kukull WA. Education, cognitive function, and severity of neuropathology in Alzheimer disease. Neurology 2007 Dec 26. [Epub ahead of print].

Friedland RP, Fritsch T, Smyth KA, Koss E, Lerner AJ, Chen CH, Petot GJ, Debanne SM. Patients with Alzheimer's disease have reduced activities in midlife compared with healthy control-group members. Proceedings of the National Academy of Sciences 2001;98(6): 3440-5.

Wilson RS, Mendes de Leon CF, Barnes LL, Schneider JA, Bienias JL, Evans DA, Bennett DA. Participation in cognitively stimulating activities and risk of incident Alzheimer's disease. JAMA 2002;287(6): 742-8.


Randi Fredricks has a Doctorate in Naturopathy and a Masters in Psychology. She runs her own natural health business, counsels clients at Recovery Connections in San Jose, California and does long distance phone consultations. Visit her website at www.randifredricks.com or contact her online. This article is from Randi Fredricks' book Healing & Wholeness: Complementary and Alternative Therapies for Mental Health. Copyright © 2008. All rights reserved. No part of this article or website may be reproduced in any form or by any electronic or mechanical means, including information storage and retrieval systems.






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